RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-1269a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
dual-lucimmunofluorescenceerase reporter assay; qRT-PCR; etc.
Target
NA
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
Upregulation of microRNA-126 in hepatic stellate cells may affect pathogenesis of liver fibrosis through the NF-KB pathway
Year
2015
Function
Ash1 and ezh2 protein expression was significantly elevated in fibrotic liver and significantly decreased in mmmp-9- and hgf-treated compared to saline-treated fibrotic livers with further reduction in the mmmp-9 group.